Le Service commun de cytométrie et de microscopie confocale est créé en tant qu'une plateforme scientifique commune pour les chercheurs du CRC au début de l'année 1998. (L’achat initial d’équipements était supervisé par les profs. Dupuis, Payet, Hunting et Stankova mandatés par l’ensemble des chercheurs du CRC). En novembre 1998, dans le cadre d’un concours national les mêmes personnes ont formé une commission de sélection du responsable du service, qui rentrait en fonction en 1999.

Actuellement le service est supervisé par Dr. L. Volkov

Les prestations du service ont été sollicitées pour de  nombreux mémoires et thèses, demandes de subventions et présentations lors des conférences ou des séminaires. Plus d’une centaine d’étudiants ont reçu la formation complète en cytométrie et/ou imagerie et certains sont devenus des professionnels du domaine au sein d’équipes académiques ou de sociétés privées.

Le nombre d’articles publiés à l’aide de service est d’au moins 185.
- FACScan - Confocal - Trieur
- Epifluorescence- HistoScan

2016

185 (17) McCoy M, Poliquin-Duchesneau D, Corbin F. Molecular dynamics of FMRP and other RNA-binding proteins in MEG-01 differentiation: the role of mRNP complexes in non-neuronal development. Biochem Cell Biol. 2016; 94: 597 184 (16) Génier S, Degrandmaison J, Moreau P, Labrecque P, Hébert TE, Parent JL. Regulation of GPCR Expression through an interaction with CCT7, a subunit of the CCT/TRiC Complex. Mol Biol Cell. 2016; 27: 3800 183 (15) Shi M, Paquette B, Thippayamontri T, Gendron L, Guérin B, Sanche L. Increased radiosensitivity of colorectal tumors with intra-tumoral injection of low dose of gold nanoparticles. Int J Nanomedicine. 2016; 11: 5323 182 (14) Bobbala D, Orkhis S, Kandhi R, Ramanathan S, Ilangumaran S. Interleukin-21-dependent modulation of T cell antigen receptor reactivity towards low affinity peptide ligands in autoreactive CD8+ T lymphocytes. Cytokine. 2016; 85: 83 181 (13) Beaudoin S, Rondeau A, Martel O, Bonin MA, van Lier JE, Leyton JV. ChAcNLS, a Novel Modification to Antibody-Conjugates Permitting Target Cell-Specific Endosomal Escape, Localization to the Nucleus, and Enhanced Total Intracellular Accumulation. Mol Pharm. 2016; 13: 1915 180 (12) Shi M, Fortin D, Paquette B, Sanche L. Convection-enhancement delivery of liposomal formulation of oxaliplatin shows less toxicity than oxaliplatin yet maintains a similar median survival time in F98 glioma-bearing rat model. Invest New Drugs. 2016 Jun;34(3):269-76 179 (11) Charbonneau M, Lavoie RR, Lauzier A, Harper K, McDonald PP, Dubois CM. Platelet-Derived Growth Factor Receptor Activation Promotes the Prodestructive Invadosome-Forming Phenotype of Synoviocytes from Patients with Rheumatoid Arthritis. J Immunol. 2016; 196: 3264 178 (10) Chen XL, Serrano D, Ghobadi F, Mayhue M, Hoebe K, Ilangumaran S, Ramanathan S. TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5). PLoS One. 2016; 11:e0151837 177 (9) Bobbala D, Mayhue M, Menendez A, Ilangumaran S, Ramanathan S. Trans-presentation of interleukin-15 by interleukin-15 receptor alpha is dispensable for the pathogenesis of autoimmune type 1 diabetes. Cell Mol Immunol. 2016 Feb 8 176 (8) Cepero-Donates Y, Lacraz G, Ghobadi F, Rakotoarivelo V, Orkhis S, Mayhue M, Chen YG, Rola-Pleszczynski M, Menendez A, Ilangumaran S, Ramanathan S. Interleukin-15-mediated inflammation promotes non-alcoholic fatty liver disease. Cytokine. 2016; 82: 102 175 (7) Bobbala D, Kandhi R, Chen X, Mayhue M, Bouchard E, Yan J, Knecht H, Barabé F, Ramanathan S, Ilangumaran S. Interleukin-15 deficiency promotes the development of T-cell acute lymphoblastic leukemia in non-obese diabetes mice with severe combined immunodeficiency. Leukemia. 2016; 30: 1749 174 (6) Yeganeh M, Gui Y, Kandhi R, Bobbala D, Tobelaim WS, Saucier C, Yoshimura A, Ferbeyre G, Ramanathan S, Ilangumaran S. Suppressor of cytokine signaling 1-dependent regulation of the expression and oncogenic functions of p21CIP1/WAF1 in the liver. Oncogene. 2016; 35: 4200 173 (5) Kandhi R, Bobbala D, Yeganeh M, Mayhue M, Menendez A, Ilangumaran S. Negative regulation of the hepatic fibrogenic response by suppressor of cytokine signaling 1. Cytokine. 2016; 82: 58 172 (4) Kwiatkowska A, Couture F, Levesque C, Ly K, Beauchemin S, Desjardins R, Neugebauer W, Dory YL, Day R. Novel Insights into Structure-Activity Relationships of N-Terminally Modified PACE4 Inhibitors. ChemMedChem. 2016; 11: 289 171 (3) Cepero-Donates Y, Rakotoarivelo V, Mayhue M, Ma A, Chen YG, Ramanathan S. Homeostasis of IL-15 dependent lymphocyte subsets in the liver. Cytokine. 2016; 82: 95 170 (2) McManus S, Bisson M, Chamberland R, Roy M, Nazari S, Roux S. Autophagy and Phospho-Inositide Dependent Kinase 1 (PDK1) -Related Kinome in Pagetic Osteoclasts. J Bone Miner Res. 2016; 31: 1334 169 (1) Lauzier A, Lavoie RR, Charbonneau M, Gouin-Boisvert B, Harper K, Dubois CM. Snail Is a Critical Mediator of Invadosome Formation and Joint Degradation in Arthritis. Am J Pathol. 2016; 186: 359

2015

168 (15) Desmarais G, Charest G, Fortin D, Bujold R, Mathieu D, Paquette B. Cyclooxygenase-2 inhibitor prevents radiation-enhanced infiltration of F98 glioma cells in brain of Fischer rat. Int J Radiat Biol. 2015; 91: 624 167 (14) Sylvain-Prévost S, Ear T, Simard FA, Fortin CF, Dubois CM, Flamand N, McDonald PP. Activation of TAK1 by Chemotactic and Growth Factors, and Its Impact on Human Neutrophil Signaling and Functional Responses. J Immunol. 2015; 195: 5393 166 (13) Gharagozloo M, Mahvelati TM, Imbeault E, Gris P, Zerif E, Bobbala D, Ilangumaran S, Amrani A, Gris D. The nod-like receptor, Nlrp12, plays an anti-inflammatory role in experimental autoimmune encephalomyelitis. J Neuroinflammation. 2015; 12: 198 165 (12) Meunier I, Morisseau O, Garneau É, Marois I, Cloutier A, Richter MV. Infection with a Mouse-Adapted Strain of the 2009 Pandemic Virus Causes a Highly Severe Disease Associated with an Impaired T Cell Response. PLoS One. 2015; 10: e0138055 164 (11) Chagnon F, Bourgouin A, Lebel R, Bonin MA, Marsault E, Lepage M, Lesur O. Smart imaging of acute lung injury: exploration of myeloperoxidase (MPO) activity using in vivo endoscopic confocal fluorescence microscopy (ECFM). Am J Physiol Lung Cell Mol Physiol. 2015; 309: L543 163 (10) Simard FA, Cloutier A, Ear T, Vardhan H, McDonald PP. MEK-independent ERK activation in human neutrophils and its impact on functional responses. J Leukoc Biol. 2015 Oct;98(4):565-73 162 (9) Roy LO, Poirier MB, Fortin D. Chloroquine inhibits the malignant phenotype of glioblastoma partially by suppressing TGF-beta. Invest New Drugs. 2015; 33: 1020 161 (8) Lacraz G, Rouleau AJ, Couture V, Söllrald T, Drouin G, Veillette N, Grandbois M, Grenier G. Increased Stiffness in Aged Skeletal Muscle Impairs Muscle Progenitor Cell Proliferative Activity. PLoS One. 2015; 10: e0136217 160 (7) Traboulsi H, Larkin H, Bonin MA, Volkov L, Lavoie CL, Marsault É. Macrocyclic cell penetrating peptides: a study of structure-penetration properties. Bioconjug Chem. 2015; 26: 405 159 (6) Shi M1, Fortin D, Sanche L, Paquette B. Convection-enhancement delivery of platinum-based drugs and LipoplatinTM to optimize the concomitant effect with radiotherapy in F98 glioma rat model. Invest New Drugs. 2015 2015; 33: 555 158 (5) Levesque C, Couture F, Kwiatkowska A, Desjardins R, Guérin B, Neugebauer WA, Day R. PACE4 inhibitors and their peptidomimetic analogs block prostate cancer tumor progression through quiescence induction increased apoptosis and impaired neovascularisation. Oncotarget. 2015; 6: 3680 157 (4) Trensz F, Lucien F, Couture V, Söllrald T, Drouin G, Rouleau AJ, Grandbois M, Lacraz G, Grenier G. Increased microenvironment stiffness in damaged myofibers promotes myogenic progenitor cell proliferation. Skelet Muscle. 2015; 5: 5 156 (3) Marchand B, Arsenault D, Raymond-Fleury A, Boisvert FM, Boucher MJ. Glycogen Synthase Kinase-3 (GSK3) inhibition induces pro-survival autophagic signals in human pancreatic cancer cells. J Biol Chem. 2015; 290: 5592 155 (2) Denhez B, Lizotte F, Guimond MO, Jones N, Takano T, Geraldes P. Increased SHP-1 Expression by High Glucose Levels Reduces Nephrin Phosphorylation in Podocytes. J Biol Chem. 2015; 290: 350 154 (1) Downey J, Lauzier D, Kloen P, Klarskov K, Richter M, Hamdy R, Faucheux N, Scimè A, Balg F, Grenier G. Prospective heterotopic ossification progenitors in adult human skeletal muscle. Bone. 2015; 71: 164

2014

153 (12) Allard-Chamard H, Haroun S, de Brum-Fernandes AJ. Secreted phospholipase A2 type II is present in Paget's disease of bone and modulates osteoclastogenesis, apoptosis and bone resorption of human osteoclasts independently of its catalytic activity in vitro. Prostaglandins Leukot Essent Fatty Acids. 2014; 90: 39 152 (11) Picard-Jean F, Bouchard S, Larivée G, Bisaillon M. The intracellular inhibition of HCV replication represents a novel mechanism of action by the innate immune Lactoferrin protein. Antiviral Res. 2014; 111: 13 151 (10) Matte I, Lane D, Boivin M, Rancourt C, Piché A. MUC16 mucin (CA125) attenuates TRAIL-induced apoptosis by decreasing TRAIL receptor R2 expression and increasing c-FLIP expression. BMC Cancer. 2014; 14: 234 150 (9) Lucien F, Harper K, Pelletier PP, Volkov L, Dubois CM. Simultaneous pH measurement in endocytic and cytosolic compartments in living cells using confocal microscopy. J Vis Exp. 2014; 86 149 (8) Ly K, Saavedra YG, Canuel M, Routhier S, Desjardins R, Hamelin J, Mayne J, Lazure C, Seidah NG, Day R. Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9. J Biol Chem. 2014; 289: 17732 148 (7) Gagnon H, Beauchemin S, Kwiatkowska A, Couture F, D'Anjou F, Levesque C, Dufour F, Desbiens AR, Vaillancourt R, Bernard S, Desjardins R, Malouin F, Dory YL,Day R. Optimization of furin inhibitors to protect against the activation of influenza hemagglutinin H5 and Shiga toxin. J Med Chem. 2014; 57: 29 147 (6) Béland M, Bédard M, Tremblay G, Lavigne P, Roucou X. Abeta induces its own prion protein N-terminal fragment (PrPN1)-mediated neutralization in amorphous aggregates. Neurobiol Aging. 2014; 35: 1537 146 (5) Lachance V1, Degrandmaison J, Marois S, Robitaille M, Génier S, Nadeau S, Angers S, Parent JL. Ubiquitylation and activation of a Rab GTPase is promoted by a beta2AR-HACE1 complex. J Cell Sci. 2014; 127: 111 145 (4) Binda C, Génier S, Cartier A, Larrivée JF, Stankova J, Young JC, Parent JL. A G protein-coupled receptor and the intracellular synthase of its agonist functionally cooperate. J Cell Biol 2014; 204: 377 144 (3) Allard-Chamard H, Dufort P, Haroun S, de Brum-Fernandes AJ. Cytosolic phospholipase A2 and eicosanoids modulate life, death and function of human osteoclasts in vitro. Prostaglandins Leukot Essent Fatty Acids. 2014; 90: 117 143 (2) Le Page A, Fortin C, Garneau H, Allard N, Tsvetkova K, Tan CT, Larbi A, Dupuis G, Fülöp T. Downregulation of inhibitory SRC Homology 2 Domain-containing Phosphatase-1 (SHP-1) leads to recovery of T cell responses in elderly. Cell Commun Signal. 2014; 12: 2 142 (1) Kwiatkowska A, Couture F, Levesque C, Ly K, Desjardins R, Beauchemin S, Prahl A, Lammek B, Neugebauer W, Dory YL, Day R. Design, Synthesis, and Structure-Activity Relationship Studies of a Potent PACE4 Inhibitor. J Med Chem. 2014; 57: 98

2013

141 (17) Lizotte F, Paré M, Denhez B, Leitges M, Guay A, Geraldes P. PKC-delta impaired vessel formation and angiogenic factor expression in diabetic ischemic limbs. Diabetes. 2013 ;62: 2948 140 (16) Roostaee A, Beaudoin S, Staskevicius A, Roucou X. Aggregation and neurotoxicity of recombinant α-synuclein aggregates initiated by dimerization. Mol Neurodegener. 2013; 8: 5 139 (15) Mayer TZ, Simard FA, Cloutier A, Vardhan H, Dubois CM, McDonald PP. The p38-MSK1 Signaling Cascade Influences Cytokine Production through CREB and C/EBP Factors in Human Neutrophils. J Immunol. 2013; 191: 4299 138 (14) Chen XL, Bobbala D, Rodriguez GM, Mayhue M, Chen YG, Ilangumaran S, Ramanathan S Induction of autoimmune diabetes in non-obese diabetic mice requires interleukin-21-dependent activation of autoreactive CD8⁺ T cells. Clin Exp Immunol. 2013; 173: 184 137 (13) Vanderperre B, Lucier JF, Bissonnette C, Motard J, Tremblay G, Vanderperre S, Wisztorski M, Salzet M, Boisvert FM, Roucou X. Direct detection of alternative open reading frames translation products in human significantly expands the proteome. PLoS One. 2013; 8: e70698 136 (12) Chen XL, Bobbala D, Rodriguez GM, Mayhue M, Chen YG, Ilangumaran S, Ramanathan S. Induction of autoimmune diabetes in NOD mice requires IL-21-dependent activation autoreactive CD8+ T cells Clin Exp Immunol. 2013; 173: 184 135 (11) Roy SJ, Glazkova I, Fréchette L, Iorio-Morin C, Binda C, Pétrin D, Trieu P, Robitaille M, Angers S, Hébert TE, Parent JL Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability. Mol Endocrinol. 2013; 27: 1245 134 (11) Bergeron D, Lapointe C, Bissonnette C, Tremblay G, Motard J, Roucou X. An Out-of-frame Overlapping Reading Frame in the Ataxin-1 Coding Sequence Encodes a Novel Ataxin-1 Interacting Protein. J Biol Chem. 2013; 288: 21824 133 (10) Forget KJ, Tremblay G, Roucou X.p53 Aggregates Penetrate Cells and Induce the Co-Aggregation of Intracellular p53. PLoS One. 2013 ; 8: e69242 132 (9) Labrecque P, Roy SJ, Fréchette L, Iorio-Morin C, Gallant MA, Parent JL. Inverse Agonist and Pharmacochaperone Properties of MK-0524 on the Prostanoid DP1 Receptor. PLoS One. 2013; 8: e65767 131 (8) Fortin CF, Mayer TZ, Cloutier A, McDonald PP. Translational control of human neutrophil responses by MNK1. J Leukoc Biol. 2013; 94: 693 130 (7) Beaulieu A, Gravel É, Cloutier A, Marois I, Colombo É, Désilets A, Verreault C, Leduc R, Marsault É, Richter MV. Matriptase proteolytically activates influenza virus and promotes multicycle replication in the human airway epithelium. J Virol. 2013; 87: 4237 129 (6) Gagnon H, Refaie S, Gagnon S, Desjardins R, Salzet M, Day R. Proprotein Convertase 1/3 (PC1/3) in the Rat Alveolar Macrophage Cell Line NR8383: Localization, Trafficking and Effects on Cytokine Secretion. PLoS One. 2013; 8: e61557 128 (5) Chen XL, Serrano D, Mayhue M, Wieden HJ, Stankova J, Boulay G, Ilangumaran S, Ramanathan S. GTPase of the immune-associated nucleotide-binding protein 5 (GIMAP5) regulates calcium influx in T-lymphocytes by promoting mitochondrial calcium accumulation. Biochem J. 2013; 449: 353 127 (4) Drapeau N, Lizotte F, Denhez B, Guay A, Kennedy CR, Geraldes P. Expression of SHP-1 induced by hyperglycemia prevents insulin actions in podocytes. Am J Physiol Endocrinol Metab. 2013; 304: E1188-98 126 (3) Arsenault D, Brochu-Gaudreau K, Charbonneau M, Dubois CM. HDAC6 Deacetylase Activity Is Required for Hypoxia-Induced Invadopodia Formation and Cell Invasion. PLoS One. 2013; 8: e55529 125 (2) Maria Rodriguez G, D'Urbano D, Bobbala D, Lin Chen X, Yeganeh M, Ramanathan S, Ilangumaran S. SOCS1 prevents potentially skin-reactive cytotoxic T lymphocytes from gaining the ability to cause inflammatory lesions. J Invest Dermatol. 2013; 133: 2013 124 (1) Durand M, Komarova SV, Bhargava A, Li K, Fiorino C, Maria O, Nabavi N, Manolson MF, Harrison RE, Jeffrey Dixon S, Sims SM, Mizianty MJ, Kurgan L, Haroun S, Boire G, de Fatima Lucena-Fernandes M, Brum-Fernandes AJ. Monocytes from patients with osteoarthritis display increased osteoclastogenesis and bone resorption: the In Vitro osteoclast differentiation in arthritis (IODA) study. Arthritis Rheum. 2013; 65: 148

2012

123 (18) Berrougui H, Loued S, Khalil A. Purified human paraoxonase-1 interacts with plasma membrane lipid rafts and mediates cholesterol efflux from macrophages. Free Radic Biol Med. 2012; 52: 1372 122 (17) Elkoreh G, Blais V, Béliveau E, Guillemette G, Denault JB. Type 1 inositol-1,4,5-trisphosphate receptor is a late substrate of caspases during apoptosis. J Cell Biochem. 2012; 113: 2775 121 (16) Goncharenko-Khaider N, Matte I, Lane D, Rancourt C, Piché A. Ovarian cancer ascites increase Mcl-1 expression in tumor cells through ERK1/2-Elk-1 signaling to attenuate TRAIL-induced apoptosis. Mol Cancer. 2012 ; 11:84 120 (15) Couture F, D'Anjou F, Desjardins R, Boudreau F, Day R. Role of proprotein convertases in prostate cancer progression. Neoplasia. 2012 ; 14: 1032 119 (14) Levesque C, Fugère M, Kwiatkowska A, Couture F, Desjardins R, Routhier S, Moussette P, Prahl A, Lammek B, Appel JR, Houghten RA, D'Anjou F, Dory YL, Neugebauer W, Day R. The Multi-Leu Peptide Inhibitor Discriminates Between PACE4 and Furin And Exhibits Antiproliferative Effects On Prostate Cancer Cells. J Med Chem. 2012 Dec 13;55(23):10501 118 (13) Catala M, Aksouh L, Abou Elela S. RNA-dependent regulation of the cell wall stress response. Nucleic Acids Res. 2012; 40: 7507 117 (12) Desmarais G, Fortin D, Bujold R, Wagner R, Mathieu D, Paquette B. Infiltration of glioma cells in brain parenchyma stimulated by radiation in the F98/Fischer rat model. Int J Radiat Biol. 2012; 88: 565 116 (11) Tippayamontri T, Kotb R, Paquette B, Sanche L Synergism in Concomitant Chemoradiotherapy of Cisplatin and Oxaliplatin and their Liposomal Formulation in the Human Colorectal Cancer HCT116 Model. Anticancer Res; 32: 4395. 115 (10) Côté J, Bovenzi V, Savard M, Dubuc C, Fortier A, Neugebauer W, Tremblay L, Müller-Esterl W, Tsanaclis AM, Lepage M, Fortin D, Gobeil F Jr. Induction of selective blood-tumor barrier permeability and macromolecular transport by a biostable kinin B1 receptor agonist in a glioma rat model. PLoS One. 2012; 7: e37485 114 (9) Béland M, Motard J, Barbarin A, Roucou X. PrPC Homodimerization Stimulates the Production of PrPC Cleaved Fragments PrPN1 and PrPC1. J Neurosci. 2012; 32: 13255 113 (8) Lauzier A, Charbonneau M, Paquette M, Harper K, Dubois CM. Transglutaminase 2 cross-linking activity is linked to invadopodia formation and cartilage breakdown in arthritis. Arthritis Res Ther. 2012; 14: R159 112 (7) Bobbala D, Chen XL, Leblanc C, Mayhue M, Stankova J, Tanaka T, Chen YG, Ilangumaran S, Ramanathan S. Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the NOD mouse. Diabetologia. 2012; 55: 3010 111 (6) Refaie S, Gagnon S, Gagnon H, Desjardins R, D'Anjou F, D'Orléans-Juste P, Zhu X, Steiner DF, Seidah NG, Lazure C, Salzet M, Day R. Disruption of PC1/3 expression in mice causes innate immune defects and uncontrolled cytokine secretion. J Biol Chem 2012; 287: 14703 110 (5) Arsenault D, Lucien F, Dubois CM. Hypoxia enhances cancer cell invasion through relocalization of the proprotein convertase furin from the trans-Golgi network to the cell surface. J Cell Physiol. 2012; 227: 789 109 (4) Khalil A, Berrougui H, Pawelec G, Fulop T. Impairment of the ABCA1 and SR-BI-mediated cholesterol efflux pathways and HDL anti-inflammatory activity in Alzheimer's disease. Mech Ageing Dev. Mech Ageing Dev. 2012; 133: 20 108 (3) Loued S, Isabelle M, Berrougui H, Khalil A. The anti-inflammatory effect of paraoxonase 1 against oxidized lipids depends on its association with high density lipoproteins. Life Sci. 2012; 90: 82 107 (2) Iorio-Morin C, Germain P, Roy S, Génier S, Labrecque P, Parent JL. Thromboxane A(2) modulates cisplatin-induced apoptosis through a Siva1-dependent mechanism. Cell Death Differ. 2012; 19: 1347 106 (1) Grbic DM, Degagn E, Larrive JF, Bilodeau MS, Vinette V, Arguin G, Stankova J, Gendron FP. P2Y(6) receptor contributes to neutrophil recruitment to inflamed intestinal mucosa by increasing CXC chemokine ligand 8 expression in an AP-1-dependent manner in epithelial cells. Inflamm Bowel Dis. 2012; 18: 1456

2011

105 (18) Lucien F, Brochu-Gaudreau K, Arsenault D, Harper K, Dubois CM. Hypoxia-Induced Invadopodia Formation Involves Activation of NHE-1 by the p90 Ribosomal S6 Kinase (p90RSK). PLoS One. 2011; 6: e28851 104 (17) D'Anjou F, Routhier S, Perreault JP, Latil A, Bonnel D, Fournier I, Salzet M, Day R. Molecular Validation of PACE4 as a Target in Prostate Cancer. Transl Oncol. 2011; 4:157 103 (16) Prinos P, Garneau D, Lucier JF, Gendron D, Couture S, Boivin M, Brosseau JP, Lapointe E, Thibault P, Durand M, Tremblay K, Gervais-Bird J, Nwilati H, Klinck R, Chabot B, Perreault JP, Wellinger RJ, Elela SA. Alternative splicing of SYK regulates mitosis and cell survival. Nat Struct Mol Biol. 2011; 18: 673 102 (15) Lachance V, Cartier A, Genier S, Munger S, Germain P, Labrecque P, Parent JL Regulation of {beta}2-adrenergic receptor maturation and anterograde trafficking by an interaction with RAB geranylgeranyltransferase: modulation of RAB geranylgeranylation by the receptor. J Biol Chem. 2011; 286: 40802 101 (14) Poulin S, Thompson C, Thivierge M, Véronneau S, McMahon S, Dubois CM, Stankova J, Rola-Pleszczynski M. Cysteinyl-leukotrienes induce vascular endothelial growth factor production in human monocytes and bronchial smooth muscle cells. Clin Exp Allergy. 2011; 41: 204 100 (13) Bah A, Gilson E, Wellinger RJ. Telomerase is required to protect chromosomes with vertebrate-type T2AG3 3' ends in Saccharomyces cerevisiae. J Biol Chem 2011; 286: 27132 99 (12) Cartier A, Parent A, Labrecque P, Laroche G, Parent JL. WDR36 acts as a scaffold protein tethering a G-protein-coupled receptor, G{alpha}q and phospholipase C{beta} in a signalling complex. J Cell Sci 2011; 124: 3292 98 (11) Lemay R, Archambault M, Tremblay L, Bujold R, Lepage M, Paquette B. Irradiation of normal mouse tissue increases the invasiveness of mammary cancer cells. Int J Radiat Biol 2011; 87: 472 97 (10) Fortin CF, Cloutier A, Ear T, Sylvain-Prévost S, Mayer TZ, Bouchelaghem R, McDonald PP. A class IA PI3K controls inflammatory cytokine production in human neutrophils. Eur J Immunol. 2011; 41: 1709 96 (9) Vanderperre B, Staskevicius AB, Tremblay G, McCoy M, O'Neill MA, Cashman NR, Roucou X. An overlapping reading frame in the PRNP gene encodes a novel polypeptide distinct from the prion protein. FASEB J. 2011; 25 :2373 95 (8) Millau JF, Bandele OJ, Perron J, Bastien N, Bouchard EF, Gaudreau L, Bell DA, Drouin R. Formation of stress-specific p53 binding patterns is influenced by chromatin but not by modulation of p53 binding affinity to response elements. Nucleic Acids Res. 2011; 26:116 94 (7) Maloum F, Allaire JM, Gagné-Sansfaçon J, Roy E, Belleville K, Sarret P, Morisset J, Carrier JC, Mishina Y, Kaestner KH, Perreault N. Epithelial BMP signaling is required for proper specification of epithelial cell lineages and gastric endocrine cells. Am J Physiol Gastrointest Liver Physiol. 2011; 300: G1065-79 93 (6) Ramanathan S, Dubois S, Chen XL, Leblanc C, Ohashi PS, Ilangumaran S. Exposure to IL-15 and IL-21 Enables Autoreactive CD8 T Cells To Respond to Weak Antigens and Cause Disease in a Mouse Model of Autoimmune Diabetes. J Immunol. 2011; 186: 5131 92 (5) Lauzier A, Charbonneau M, Harper K, Jilaveanu-Pelmus M, Dubois CM. Formation of invadopodia-like structures by synovial cells promotes cartilage breakdown in arthritis. Involvement of the protein tyrosine kinase src. Arthritis Rheum. 2011; 63: 1591 91 (4) Mathurin K, Gallant MA, Germain P, Allard-Chamard H, Brisson J, Iorio-Morin C, de Brum-Fernandes A, Caron MG, Laporte SA, Parent JL. An interaction between L-prostaglandin D synthase and arrestin increases PGD2 production. J Biol Chem. 2011; 286: 2696 90 (3) Brochu-Bourque A, Veronneau S, Rola-Pleszczynski M, Stankova J. Differential signalling defects associated with the M201V polymorphism in the cysteinyl leukotriene type 2 receptor. J Pharmacol Exp Ther. 2011; 336: 431 89 (2) Durand M, Boire G, Komarova SV, Dixon SJ, Sims SM, Harrison RE, Nabavi N, Maria O, Manolson MF, Mizianty M, Kurgan L, de Brum-Fernandes AJ. The increased in vitro osteoclastogenesis in patients with rheumatoid arthritis is due to increased percentage of precursors and decreased apoptosis - The In Vitro Osteoclast Differentiation in Arthritis (IODA) study. Bone. 2011; 48: 588 88 (1) Leblanc E, Trensz F, Haroun S, Drouin G, Bergeron E, Penton CM, Montanaro F, Roux S, Faucheux N, Grenier G. BMP9-Induced muscle heterotopic ossification requires changes to the skeletal muscle microenvironment. J Bone Miner Res. 2011; 26:116

2010

87 (17) Sukmana I, Vermette P. The effects of co-culture with fibroblasts and angiogenic growth factors on microvascular maturation and multi-cellular lumen formation in HUVEC-oriented polymer fibre constructs. Biomaterials. 2010; 31: 5091 86 (16) Parent A, Roy SJ, Iorio-Morin C, Lepine MC, Labrecque P, Gallant MA, Slipetz D, Parent JL. ANKRD13C acts as a molecular chaperone for G protein-coupled receptors. J Biol Chem. 2010; 285: 40838 85 (15) Goncharenko-Khaider N, Lane D, Matte I, Rancourt C, Piché A. The inhibition of Bid expression by Akt leads to resistance to TRAIL-induced apoptosis in ovarian cancer cells. Oncogene. 2010; 29: 5523 84 (14) Faucher D, Wellinger RJ. Methylated H3K4, a transcription-associated histone modification, is involved in the DNA damage response pathway. PLoS Genet. 2010; 6: e1001082 83 (13) Ramanathan S, Dubois S, Gagnon J, Leblanc C, Mariathasan S, Ferbeyre G, Rottapel R, Ohashi PS, Ilangumaran S. Regulation of cytokine-driven functional differentiation of CD8 T cells by suppressor of cytokine signaling 1 controls autoimmunity and preserves their proliferative capacity toward foreign antigens. J Immunol. 2010; 185: 357 82 (12) Trensz F, Haroun S, Cloutier A, Richter MV, Grenier G. A Muscle Resident Cell Population Promotes Fibrosis in Hindlimb Skeletal Muscles of Mdx Mice Through the Wnt Canonical Pathway. Am J Physiol Cell Physiol. 2010; 299: C939 81 (11). Ear T, Fortin CF, Simard FA, McDonald PP. Constitutive association of TGF-beta-activated kinase 1 with the IkappaB kinase complex in the nucleus and cytoplasm of human neutrophils and its impact on downstream processes J Immunol. 2010; 184: 3897 80 (10). Harper K, Arsenault D, Boulay-Jean S, Lauzier A, Lucien F, Dubois CM.Autotaxin promotes cancer invasion via the lysophosphatidic acid receptor 4: participation of the cyclic AMP/EPAC/Rac1 signaling pathway in invadopodia formation. Cancer Res. 2010; 70: 4634 79 (9). Fortin CF, Sohail A, Sun Q, McDonald PP, Fridman R, Fülöp T. MT6-MMP is present in lipid rafts and faces inward in living human PMNs but translocates to the cell surface during neutrophil apoptosis. Int Immunol. 2010; 22: 637 78 (8). Chamoux E, Bisson M, Payet MD, Roux S.TRPV-5 mediates a RANK ligand-induced increase in cytosolic Ca2+ in human osteoclasts and downregulates bone resorption. J Biol Chem. 2010; 285: 25354 77 (7). Bellavance MA, Poirier MB, Fortin D.Uptake and intracellular release kinetics of liposome formulations in glioma cells. Int J Pharm. 2010; 395: 251 76 (6). Vodenicharov MD, Laterreur N, Wellinger RJ.Telomere capping in non-dividing yeast cells requires Yku and Rap1. EMBO J. 2010; 29: 3007 75 (5). Toussaint M, Wellinger RJ, Conconi A. Differential participation of homologous recombination and nucleotide excision repair in yeast survival to ultraviolet light radiation. Mutat Res. 2010; 698: 52 74 (4). Lane D, Goncharenko-Khaider N, Rancourt C, Piché A. Ovarian cancer ascites protects from TRAIL-induced cell death through alphavbeta5 integrin-mediated focal adhesion kinase and Akt activation.Oncogene. 2010; 29: 3519 73 (3). Roy SJ, Parent A, Gallant MA, de Brum-Fernandes AJ, Stanková J, Parent JL. Characterization of C-terminal tail determinants involved in CRTH2 receptor trafficking: identification of a recycling motif. Eur J Pharmacol. 2010; 630: 10 72 (2). Cauchon N, Ali H, Hasséssian HM, van Lier JE. Structure-activity relationships of mono-substituted trisulfonated porphyrazines for the photodynamic therapy (PDT) of cancer. Photochem Photobiol Sci. 2010; 9: 33 71 (1). Bovenzi V, Savard M, Morin J, Cuerrier CM, Grandbois M, Gobeil F Jr. Bradykinin protects against brain microvascular endothelial cell death induced by pathophysiological stimuli. J Cell Physiol. 2010; 222: 168

2009

70 (13). Siqueira JM, Gazola AC, Farias MR, Volkov L, Rivard N, de Brum-Fernandes AJ, Ribeiro-do-Valle RM. Evaluation of the antitumoral effect of dihydrocucurbitacin-B in both in vitro and in vivo models. Cancer Chemother Pharmacol. 2009; 64: 52 69 (12). Poisson C, Rollin S, Véronneau S, Bousquet SM, Larrivée JF, Le Gouill C, Boulay G, Stankova J, Rola-Pleszczynski M. Caveolae facilitate but are not essential for platelet-activating factor-mediated calcium mobilization and extracellular signal-regulated kinase activation.J Immunol. 2009; 183: 2747 68 (11). Battista MC, Roberge C, Martinez A, Gallo-Payet N. 24-dehydrocholesterol reductase/seladin-1: a key protein differentially involved in adrenocorticotropin effects observed in human and rat adrenal cortex. Endocrinology. 2009; 150: 4180 67 (9). Picard N, Ali H, van Lier JE, Klarskov K, Paquette B. Bromines on N-allyl position of cationic porphyrins affect both radio- and photosensitizing properties. Photochem Photobiol Sci. 2009; 8: 224-32. 66 (8). Boivin M, Lane D, Piché A, Rancourt C. CA125 (MUC16) tumor antigen selectively modulates the sensitivity of ovarian cancer cells to genotoxic drug-induced apoptosis. Gynecol Oncol. 2009 Sep Epub 65 (7). Ali H, Cauchon N, van Lier JE. Pd-catalyzed Heck reaction for the synthesis of isomeric metallo tetravinylsulfo phthalocyanines and their photosensitizing properties. Photochem Photobiol Sci. 2009; 8: 868 64 (6). Cloutier A, Guindi C, Larivée P, Dubois CM, Amrani A, McDonald PP. Inflammatory cytokine production by human neutrophils involves C/EBP transcription factors. J Immunol. 2009; 182: 563 63 (5). Cuerrier CM, Benoit M, Guillemette G, Jr Gobeil F, Grandbois M. Real-time monitoring of angiotensin II-induced contractile response and cytoskeleton remodeling in individual cells by atomic force microscopy. Pflugers Arch. 2009; 457: 1361 62 (3). Ilangumaran S, Forand-Boulerice M, Bousquet SM, Savard A, Rocheleau P, Chen XL, Dupuis G, Poussier P, Boulay G, Ramanathan S. Loss of GIMAP5 (GTPase of immunity-associated nucleotide binding protein 5) impairs calcium signaling in rat T lymphocytes. Mol Immunol. 2009; 46: 1256 61 (2). A. Parent, E. Hamelin, P. Germain, Parent JL. Rab11 regulates the recycling of the ?2-adrenergic receptor through a direct interaction. Biochem J. 2009; 418: 163 60 (1). Beaudoin S, Vanderperre B, Grenier C, Tremblay I, Leduc F, Roucou X. A large ribonucleoprotein particle induced by cytoplasmic PrP shares striking similarities with the chromatoid body, an RNA granule predicted to function in posttranscriptional gene regulation. Biochim Biophys Acta. 2009; 1793: 335

2008

59(11). Cuerrier CM, Chabot V, Vigneux S, Aimez V, Escher E, Gobeil Jr. F, Charrette PG, Grandbois M. Surface Plasmon Resonance Monitoring of Cell Monolayer Integrity: Implication of Signaling Pathways Involved in Actin-Driven Morphological Remodeling. Cell Mol Bioeng 2008; 1: 229 58(10). Bossé Y, Thompson C, McMahon S, Dubois CM, Stankova J, Rola-Pleszczynski M. Leukotriene D(4)-induced, epithelial cell-derived transforming growth factor beta1 in human bronchial smooth muscle cell proliferation. Clin Exp Allergy. 2008 ; 38: 113 57(9). Parent A, Laroche G, Hamelin E, Parent JL. RACK1 regulates the cell surface expression of the G protein-coupled receptor for thromboxane A(2). Traffic. 2008; 9: 394 56(8). Ear T, McDonald PP. Cytokine generation, promoter activation, and oxidant-independent NF-kappaB activation in a transfectable human neutrophilic cellular model. BMC Immunol. 2008; 9: 14 55(7). Bossé Y, Thompson C, Audette K, Stankova J, Rola-Pleszczynski M. Interleukin-4 and interleukin-13 enhance human bronchial smooth muscle cell proliferation. Int Arch Allergy Immunol. 2008; 146: 138 54(6). Leduc F, Maquennehan V, Nkoma GB, Boissonneault G. DNA damage response during chromatin remodeling in elongating spermatids of mice. Biol Reprod. 2008; 78: 324 53(5). Wilhelm E, Pellay FX, Benecke A, Bell B. TAF6delta controls apoptosis and gene expression in the absence of p53. PLoS ONE. 2008; 3: e2721 52(4). Thompson C, Cloutier A, Bossé Y, Poisson C, Larivée P, McDonald PP, Stankova J, Rola-Pleszczynski M. Signaling by the cysteinyl-leukotriene receptor 2. Involvement in chemokine gene transcription. J Biol Chem. 2008; 283: 1974 51(3). Goggin K, Beaudoin S, Grenier C, Brown AA, Roucou X. Prion protein aggresomes are poly(A)(+) ribonucleoprotein complexes that induce a PKR-mediated deficient cell stress. Biochim Biophys Acta. 2008; 1783: 479 50(2). Chagnon F, Vaidya VS, Plante GE, Bonventre JV, Bernard A, Guindi C, Lesur O. Modulation of aquaporin-2/vasopressin2 receptor kidney expression and tubular injury after endotoxin (lipopolysaccharide) challenge. Crit Care Med. 2008; 36: 3054 49(1). Beaudoin S, Goggin K, Bissonnette C, Grenier C, Roucou X. Aggresomes do not represent a general cellular response to protein misfolding in mammalian cells. BMC Cell Biol. 2008; 9: 59

2007

48. Garneau H, Alvarez L, Paquin MC, Lussier C, Rancourt C, Tremblay E, Beaulieu JF, Rivard N. Nuclear expression of E2F4 induces cell death via multiple pathways in normal human intestinal epithelial crypt cells but not in colon cancer cells. Am J Physiol Gastrointest Liver Physiol. 2007; 293: G758 47. Dupré DJ, Thompson C, Chen Z, Rollin S, Larrivée JF, Le Gouill C, Rola-Pleszczynski M, Stanková J. Inverse agonist-induced signaling and down-regulation of the platelet-activating factor receptor. Cell Signal. 2007; 19: 2068 46. Vodenicharov MD, Wellinger RJ. The cell division cycle puts up with unprotected telomeres: cell cycle regulated telomere uncapping as a means to achieve telomere homeostasis. Cell Cycle. 2007; 6: 1161 45. Lane D, Robert V, Grondin R, Rancourt C, Piché A. Malignant ascites protect against TRAIL-induced apoptosis by activating the PI3K/Akt pathway in human ovarian carcinoma cells. Int J Cancer. 2007; 121: 1227 44. Farand P, Garon A, Plante GE. Structure of large arteries: orientation of elastin in rabbit aortic internal elastic lamina and in the elastic lamellae of aortic media. Microvasc Res. 2007; 73: 95-9 43. Goggin K, Bissonnette C, Grenier C, Volkov L, Roucou X. Aggregation of cellular prion protein is initiated by proximity-induced dimerization. J Neurochem. 2007; 102: 1195 42. Keita M, Leblanc C, Andrews D, Ramanathan S. GIMAP5 regulates mitochondrial integrity from a distinct subcellular compartment. Biochem Biophys Res Commun. 2007; 361: 481 41. Laroche G, Giguere PM, Dupre E, Dupuis G, Parent JL. The N-terminal coiled-coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with Galphaq. Mol Cell Biochem. 2007; 306: 141-52. 40. Charbonneau M, Harper K, Grondin F, Pelmus M, McDonald PP, Dubois CM. Hypoxia-inducible factor mediates hypoxic and TNF alpha-induced increases in TACE/ADAM17 expression by synovial cells. J Biol Chem. 2007; 282: 33714 39. Cauchon N, Langlois R, Rousseau JA, Tessier G, Cadorette J, Lecomte R, Hunting DJ, Pavan RA, Zeisler SK, van Lier JE. PET imaging of apoptosis with (64)Cu-labeled streptavidin following pretargeting of phosphatidylserine with biotinylated annexin-V. Eur J Nucl Med Mol Imaging. 2007; 34:247-58

2006

38. Cauchon N, Nader M, Bkaily G, van Lier J, Hunting D. Photodynamic Activity of Substituted Zinc Trisulfophthalocyanines: Role of Plasma Membrane Damage. Photochem Photobiol. 2006; 82:1712 37. Chagnon F, Bentourkia M, Lecomte R, Lessard M, Lesur O. Endotoxin-induced heart dysfunction in rats: assessment of myocardial perfusion and permeability and the role of fluid resuscitation. Crit Care Med. 2006; 34: 127 36. Grenier C, Bissonnette C, Volkov L, Roucou X. Molecular morphology and toxicity of cytoplasmic prion protein aggregates in neuronal and non-neuronal cells. J Neurochem. 2006; 97: 1456 35. St-Amant C, Lussier S, Lehoux J, Laberge RM, Boissonneault G. Altered phosphorylation of topoisomerase I following overexpression in an ovarian cancer cell line. Biochem Cell Biol. 2006; 84: 55 34. Thompson C, Cloutier A, Bosse Y, Thivierge M, Gouill CL, Larivee P, McDonald PP, Stankova J, Rola-Pleszczynski M. CysLT1 receptor engagement induces activator protein-1- and NF-kappaB-dependent IL-8 expression. Am J Respir Cell Mol Biol. 2006; 35: 697 33. Hackett JA, Allard-Chamard H, Sarrazin P, de Fatima Lucena M, Gallant MA, Fortier I, Nader M, Parent JL, Bkaily G, de Brum-Fernandes AJ. Prostaglandin production by human osteoclasts in culture. J Rheumatol. 2006; 33:1320

2005

32. Cauchon N, Tian H, Langlois R, La Madeleine C, Martin S, Ali H, Hunting D, van Lier JE. Structure-photodynamic activity relationships of substituted zinc trisulfophthalocyanines. Bioconjug Chem. 2005; 16: 80 31. Chagnon F, Metz CN, Bucala R, Lesur O. Endotoxin-induced myocardial dysfunction: effects of macrophage migration inhibitory factor neutralization. Circ Res. 2005; 96: 1095 30. Gaudreault E, Thompson C, Stankova J, Rola-Pleszczynski M. Involvement of BLT1 endocytosis and Yes kinase activation in leukotriene B4-induced neutrophil degranulation. J Immunol. 2005; 174: 3617 29. Guillemette J, Caron AZ, Regimbald-Dumas Y, Arguin G, Mignery GA, Boulay G, Guillemette G. Expression of a truncated form of inositol 1,4,5-trisphosphate receptor type III in the cytosol of DT40 triple inositol 1,4,5-trisphosphate receptor-knockout cells. Cell Calcium. 2005; 37: 97 28. Laberge RM, Boissonneault G. On the nature and origin of DNA strand breaks in elongating spermatids. Biol Reprod. 2005; 73: 289 27. Larbi A, Grenier A, Frisch F, Douziech N, Fortin C, Carpentier AC, Fulop T. Acute in vivo elevation of intravascular triacylglycerol lipolysis impairs peripheral T cell activation in humans. Am J Clin Nutr. 2005; 82: 949 26. Auger-Messier M, Turgeon ES, Leduc R, Escher E, Guillemette G. The constitutively active N111G-AT1 receptor for angiotensin II modifies the morphology and cytoskeletal organization of HEK-293 cells. Exp Cell Res. 2005; 308: 188

2004

25. Chen Z, Gaudreau R, Le Gouill C, Rola-Pleszczynski M, Stanková J. Agonist-induced internalization of leukotriene B(4) receptor 1 requires G-protein-coupled receptor kinase 2 but not arrestins. Mol Pharmacol. 2004; 66: 377 24. Larbi A, Douziech N, Dupuis G, Khalil A, Pelletier H, Guerard KP, Fulop T Jr. Age-associated alterations in the recruitment of signal-transduction proteins to lipid rafts in human T lymphocytes. J Leukoc Biol. 2004; 75: 373-81 23. Larbi A, Dupuis G, Douziech N, Khalil A, Fulop T Jr. Low-grade inflammation with aging has consequences for T-lymphocyte signaling. Ann N Y Acad Sci. 2004; 1030: 125 22. Lesur O, Brisebois M, Thibodeau A, Chagnon F, Lane D, Fullop T. Role of IFN-gamma and IL-2 in rat lung epithelial cell migration and apoptosis after oxidant injury. Am J Physiol Lung Cell Mol Physiol. 2004 ; 286: L4-L14 21. Marcon L, Boissonneault G. Transient DNA strand breaks during mouse and human spermiogenesis new insights in stage specificity and link to chromatin remodeling. Biol Reprod. 2004; 70: 910 20. Sarrazin P, Hackett JA, Fortier I, Gallant MA, de Brum-Fernandes A. Role of EP3 and EP4 prostaglandin receptors in reorganization of the cytoskeleton in mature human osteoclasts. J Rheumatol. 2004; 31: 1598 19. Larbi A, Douziech N, Khalil A, Dupuis G, Gheraïri S, Guérard KP, Fülöp T Jr. Effects of methyl-beta-cyclodextrin on T lymphocytes lipid rafts with aging. Exp Gerontol. 2004; 39: 551

2003

18. Dupre DJ, Chen Z, Le Gouill C, Theriault C, Parent JL, Rola-Pleszczynski M, Stankova J. Trafficking, ubiquitination, and down-regulation of the human platelet-activating factor receptor. J Biol Chem. 2003; 278: 48228 17. Eric J, Bkaily G, Bkaily GB, Volkov L, Gabra BH, Sirois P. Des-Arg9-bradykinin increases intracellular Ca2+ in bronchoalveolar eosinophils from ovalbumin-sensitized and -challenged mice. Eur J Pharmacol. 2003; 475: 129 16. Espinosa K, Bosse Y, Stankova J, Rola-Pleszczynski M. CysLT1 receptor upregulation by TGF-beta and IL-13 is associated with bronchial smooth muscle cell proliferation in response to LTD4. J Allergy Clin Immunol. 2003; 111: 1032 15. Holleran BJ, Barbar E, Payet MD, Dupuis G. Differential recruitment of alpha2beta1 and alpha4beta1 integrins to lipid rafts in Jurkat T lymphocytes exposed to collagen type IV and fibronectin. J Leukoc Biol. 2003; 73: 243 14. Perron A, Chen ZG, Gingras D, Dupre DJ, Stankova J, Rola-Pleszczynski M. Agonist-independent desensitization and internalization of the human platelet-activating factor receptor by coumermycin-gyrase B-induced dimerization. J Biol Chem. 2003; 278: 27956 13. Richter M, Cantin AM, Beaulieu C, Cloutier A, Larivee P. Zinc chelators inhibit eotaxin, RANTES, and MCP-1 production in stimulated human airway epithelium and fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2003; 285: L719

2002

12. Allen CM, Sharman WM, La Madeleine C, van Lier JE, Weber JM. Attenuation of photodynamically induced apoptosis by an RGD containing peptide. Photochem Photobiol Sci. 2002; 1: 246 11. Chen Z, Dupre DJ, Le Gouill C, Rola-Pleszczynski M, Stankova J. Agonist-induced internalization of the platelet-activating factor receptor is dependent on arrestins but independent of G-protein activation. Role of the C terminus and the (D/N)PXXY motif. J Biol Chem. 2002; 277: 7356-62. 10. Laflamme K, Domingue O, Guillemette BI, Guillemette G. Immunohistochemical localization of type 2 inositol 1,4,5-trisphosphate receptor to the nucleus of different mammalian cells. J Cell Biochem. 2002; 85: 219 9. Laprise MH, Grondin F, Cayer P, McDonald PP, Dubois CM. Furin gene (fur) regulation in differentiating human megakaryoblastic Dami cells: involvement of the proximal GATA recognition motif in the P1 promoter and impact on the maturation of furin substrates. Blood. 2002; 100: 3578 8. Leclerc P.C., M. Auger-Messier, P. M. Lanctot, E. Escher, R. Leduc, Guillemette G. A Polyaromatic Caveolin-Binding-Like Motif in the Cytoplasmic Tail of the Type 1 Receptor for Angiotensin II Plays an Important Role in Receptor Trafficking and Signaling. Endocrinology 2002; 143: 4702 7. Marrache AM, Gobeil F Jr, Bernier SG, Stankova J, Rola-Pleszczynski M, Choufani S, Bkaily G, Bourdeau A, Sirois MG, Vazquez-Tello A, Fan L, Joyal JS, Filep JG, Varma DR, Ribeiro-Da-Silva A, Chemtob S. Proinflammatory gene induction by platelet-activating factor mediated via its cognate nuclear receptor. J Immunol. 2002; 169: 6474 6. Stankova J, Turcotte S, Harris J, Rola-Pleszczynski M. Modulation of leukotriene B4 receptor-1 expression by dexamethasone: potential mechanism for enhanced neutrophil survival. J Immunol. 2002; 168: 3570-6

2001

5. I. Fortier, C. Patry, M. Lora, R. Samadfan, A. J. de Brum-Fernandes. Immunohistochemical localization of the prostacyclin receptor (IP) human bone Prostaglandins Leukot Essent Fatty Acids. 2001; 65:79 4. Lukashova V., C. Asselin, J. J. Krolewski, M. Rola-Pleszczynski, Stankova J. G-protein-independent Activation of Tyk2 by the Platelet-activating Factor Receptor. J Biol Chem 2001; 276: 24113

2000

3. Bouffard P, Barbar E, Briere F, Boire G. Interaction cloning and characterization of RoBPI, a novel protein binding to human Ro ribonucleoproteins. RNA. 2000; 6: 66 2. Menard I., R. El Jastimi, A. Forget, L. Volkov, N. Monfino and J.E. van Lier. Evaluation of th9402-mediated photodynamic cell purging: cellular uptake and localization. American Society for Photobiology: 28th Annual Meeting, 2000, San Francisco, CA

1999

1. Chamoux E, Breault L, Lehoux JG, Gallo-Payet N. Involvement of the angiotensin II type 2 receptor in apoptosis during human fetal adrenal gland development. J Clin Endocrinol Metab. 1999; 84: 4722-30